Certain beta-blockers can decrease beta-adrenergic receptor number: I. Acute reduction in receptor number by tertatolol and bopindolol.
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منابع مشابه
Certain beta-blockers can decrease beta-adrenergic receptor number: II. Down-regulation of receptor number by alprenolol and propranolol in cultured lymphoma and muscle cells.
We have used two different cultured cell lines--S49 lymphoma cells and BC3H-1 muscle cells--to examine the regulation of beta-adrenergic receptors by receptor antagonists. Rather than an increase ("up-regulation") of receptor number that such antagonists often produce, we found that certain beta-blockers elicit a decrease ("down-regulation") of beta-adrenergic receptors. Alprenolol and proprano...
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We have used two different cultured cell lines—S49 lymphoma cells and BC3H-1 muscle cells— to examine the regulation of /3-adrenergic receptors by receptor antagonists. Rather than an increase ("up-regulation") of receptor number that such antagonists often produce, we found that certain /3-blockers elicit a decrease ("down-regulation") of beta-adrenergic receptors. Alprenolol and propranolol, ...
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ژورنال
عنوان ژورنال: Circulation Research
سال: 1988
ISSN: 0009-7330,1524-4571
DOI: 10.1161/01.res.63.2.273